Physical Optics and Biophotonics

Research details

The research in our group can be seen as a synergistic interplay of physics, biology, and chemistry. We are focused on developing imaging techniques and using them in many biological and chemical systems. The uniqueness of our approach is using not only the amplitude of the light but also its phase in order to develop new, world-class imaging systems. Optical Coherence Tomography is a great example of such a method, and we are advancing its capabilities by implementing an innovative method for removal of image distortion ― STOC (Spatio Temporal Optical Coherence manipulation), which has the potential to largely increase the quality of imaging through opaque layers, such as skin.

All projects are aimed to bring to humanity new non-invasive imaging techniques, that will enhance our understanding of nature, increase quality of life, and extend longevity.

POB Address: ICTER Headquarters, Skierniewicka 10A, 01-230 Warsaw
Phone number: +48 607 293 453
Group Leader: mwojtkowski@ichf.edu.pl
Team Coordinator: asalamonczyk@ichf.edu.pl

Research Group Leaders & Coordinators

How to see the invisible? The limits of two-photon vision

Hand holding a round-bottom flask of pink liquid beside glowing medical icons and a rainbow funnel forming a pill, illustrating drug design

21.04.2026

ICTER contributes to a global handbook of visual optics

Smiling woman in a lab holds a trial frame with optical lenses to her eye, optical bench and posters in background

16.12.2025

Two-photon Vision in AR glasses. ICTER is developing a completely new class of displays

Diagram of a head with brain, zoomed inset showing light emitter and detector probing brain tissue

28.08.2023

Physical Optics and Biophotonics

Research Group Leaders & Coordinators

Maciej Wojtkowski

Marzena Łazarczyk

Senior Researchers

Katarzyna Komar

Sławomir Tomczewski

Postdoctoral Researchers

Kamil Liżewski

Marta Mikuła-Zdańkowska

Piotr Kasprzycki

Doctoral Researchers

Maciej Standerski

Oliwia Kaczkoś

Piotr Węgrzyn

Research Technicians

Mateusz Grochalski

Tomir Domański

Former members

Agata Kotulska

Egidijus Auksorius

Jakub Bogusławski

Mounika Rapolu

Onur Çetinkaya, BEng

Piotr Ciąćka

Rafał Pietruch

Saeed Samaei

Publications

„Two-photon vision” chapter in “Handbook of Visual Optics, Volume Two”

Spatio-temporal optical coherence imaging and tomography for in vivo applications

Effect of laser-beam diameter on the visibility of two-photon stimuli

Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics

Computational aberration correction enables full-thickness retinal imaging with adaptive optics optical coherence tomography

Visual Function Loss Through Opacified Media: Comparison Between Single- and Two-Photon Vision

Modeling breast cancer dynamics through modulable small Vessel Environment Bioreactor (sVEB)

Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction

Imaging of retinal ganglion cells and photoreceptors using Spatio-Temporal Optical Coherence Tomography (STOC-T) without hardware-based adaptive optics

In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography

Method for the determination of the luminance of two-photon vision stimuli

Refining a Human Two-Photon Imaging System

Optical coherence tomography imaging by a fully integrated MOEMS endomicroscopy probe with Mirau micro-interferometer and two axis electrothermal micro-scanner using Lissajous trajectory scanning

Chirped flicker optoretinography for in vivo characterization of human photoreceptors’ frequency response to light

Two-photon vision – Seeing colors in infrared

Multiwavelength laser doppler holography (MLDH) in spatiotemporal optical coherence tomography (STOC-T)

Large reconfigurable quantum circuits with SPAD arrays and multimode fibers

Imaging the retinal and choroidal vasculature using Spatio-Temporal Optical Coherence Tomography (STOC-T)

Optimization-free method for multiple spectrometers alignment in polarization-sensitive optical coherence tomography

Comparison of repeatability of visual thresholds determination for one-and two-photon vision mechanisms

Laser pulse train parameters determine the brightness of a two-photon stimulus

Flicker optoretinography (f-ORG) with chirped frequency stimulus for retinal tissue characterisation

Spatio-temporal optical coherence tomography (STOC-T) for high-resolution imaging of the human and mouse retina in vivo

Clinical prototype of multi-spot air-puff OCT for assessment of corneal biomechanical asymmetry

In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope

Spatio-temporal optical coherence tomography (STOC-T) focal plane adjustment in the mouse retina aided by a fundus camera

Frequency characterization of human photoreceptors’ response to light with the use of chirped flicker stimulus optoretinography

High-speed, in vivo, volumetric imaging of mouse retinal tissue with spatio-temporal optical coherence tomography (STOC-T)

From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation.

Methods of determining the contrast sensitivity function for two-photon vision

Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials

Functional and Structural Imaging of Retinal Tissue with Spatio-Temporal Optical Coherence Tomography (STOC-T)

Continuous-wave parallel interferometric near-infrared spectroscopy (CW πNIRS) with a fast two-dimensional camera

Contrast Sensitivity Function of Two-Photon Vision

Towards spectral sensitivity curve for two-photon vision mechanism

Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers

Spatio-Temporal Optical Coherence Tomography provides full thickness imaging of the chorioretinal complex

You will know by its tail: a method for quantification ofheterogeneity of bacterial populations using single-cell MICprofiling

In vivo frequency characterization of human photoreceptors response to a flicker stimulus with optoretinography

Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system

Two-Photon Vision in Age-Related Macular Degeneration: ATranslational Study

Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans

Infrared- and white-light retinal sensitivity in glaucomatous neuropathy

Multimode fiber as a tool to reduce crosstalk in Fourier-domain full-field optical coherence tomography

Optical coherence tomography reveals heterogeneity of the brain tissue and vasculature in the ischemic region after photothrombotic stroke in mice

Air puff-coupled multi-spot OCT for assessment of asymmetries in corneal biomechanics

Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography

In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope

Pupillary Light Reflex induced by two-photon vision

Two-photon excited fluorescence scanning laser ophthalmoscope for in vivo imaging of the human eye

The effect of cataract on two-photon visual thresholds

Swept-sources for OCT are perceived due to two-photon vision