Zespół Obrazowania Optycznego
Badania prowadzone w naszej grupie można postrzegać jako doskonałe połączenie fizyki, biologii i chemii. Koncentrujemy się na rozwoju technik obrazowania i wykorzystaniu ich w wielu układach biologicznych i chemicznych. Unikalność naszego podejścia polega na wykorzystaniu nie tylko amplitudy światła, ale również jego fazy w celu opracowania nowych, najwyższej klasy systemów obrazowania. Doskonałym przykładem takiej metody jest Tomografia Optyczna OCT. Ponadto, wdrażamy innowacyjną metodę usuwania zniekształceń obrazu - STOC (Spatio Temporal Optical Coherence manipulation), która ma potencjał do znacznego zwiększenia jakości obrazowania przez warstwy nieprzezroczyste, takie jak skóra.
Wszystkie te projekty mają na celu dostarczenie ludzkości nowych, nieinwazyjnych technik obrazowania, które sprawią, że nasze życie będzie dłuższe, lepsze i z większym zrozumieniem natury.
POB Adres: ICTER, Skierniewicka 10A, 01-230 Warszawa, Kasprzaka 44/52, 01-224 Warszawa
Numer telefonu: +48 607 293 453
Lider Grupy: mwojtkowski@ichf.edu.pl
Koordynator Zespołu: marzena.lazarczyk@ichf.edu.pl
Kierownicy i koordynatorzy grup badawczych
Badacze podoktorscy
Publikacje
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Handbook of Visual Optics, Volume Two
„Two-photon vision” chapter in „Handbook of Visual Optics, Volume Two”
10.1201/9781032696690
2026
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Journal of Biomedical Optics
Spatio-temporal optical coherence imaging and tomography for in vivo applications
10.1117/1.JBO.31.11.113504
2026
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Optics Letters
Effect of laser-beam diameter on the visibility of two-photon stimuli
10.1364/OL.589174
2026
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Biomedical Optics Express
Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics
10.1364/BOE.596342
2026
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Biocybernetics and Biomedical Engineering
Computational aberration correction enables full-thickness retinal imaging with adaptive optics optical coherence tomography
10.1016/j.bbe.2026.02.002
2026
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Translational Vision Science & Technology
Visual Function Loss Through Opacified Media: Comparison Between Single- and Two-Photon Vision
10.1167/tvst.15.2.11
2026
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Modeling breast cancer dynamics through modulable small Vessel Environment Bioreactor (sVEB)
10.1016/j.biomaterials.2025.123441
2025
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Proceedings of the National Academy of Sciences
Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction
10.1073/pnas.2421722122
2025
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Biocybernetics and Biomedical Engineering
Imaging of retinal ganglion cells and photoreceptors using Spatio-Temporal Optical Coherence Tomography (STOC-T) without hardware-based adaptive optics
10.1016/j.bbe.2025.01.001
2025
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STAR Protocols
In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography
10.1117/1.NPh.11.4.045003
2024
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Biomedical Optics Express
Method for the determination of the luminance of two-photon vision stimuli
10.1364/BOE.525180
2024
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Investigative Ophthalmology & Visual Science
Refining a Human Two-Photon Imaging System
https://iovs.arvojournals.org/article.aspx?articleid=2795745
2024
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IEEE Sensors Journal
Optical coherence tomography imaging by a fully integrated MOEMS endomicroscopy probe with Mirau micro-interferometer and two axis electrothermal micro-scanner using Lissajous trajectory scanning
10.1109/JSEN.2024.3373223
2024
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Optics Letters
Chirped flicker optoretinography for in vivo characterization of human photoreceptors’ frequency response to light
10.1364/OL.514637
2024
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Vision Research
Two-photon vision – Seeing colors in infrared
10.1016/j.visres.2024.108404
2024
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Multiwavelength laser doppler holography (MLDH) in spatiotemporal optical coherence tomography (STOC-T)
10.1016/j.bbe.2024.03.002
2024
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Optica
Large reconfigurable quantum circuits with SPAD arrays and multimode fibers
10.1364/OPTICA.506943
2024
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Biocybernetics and Biomedical Engineering
Imaging the retinal and choroidal vasculature using Spatio-Temporal Optical Coherence Tomography (STOC-T)
10.1016/j.bbe.2023.12.002
2024
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SPIE Proceedings
Optimization-free method for multiple spectrometers alignment in polarization-sensitive optical coherence tomography
10.1117/12.2670617
2023
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Investigative Ophthalmology & Visual Science
Comparison of repeatability of visual thresholds determination for one-and two-photon vision mechanisms
https://iovs.arvojournals.org/article.aspx?articleid=2787063
2023
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Biomedical Optics Express
Laser pulse train parameters determine the brightness of a two-photon stimulus
10.1364/BOE.489890
2023
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Technical Digest Series
Flicker optoretinography (f-ORG) with chirped frequency stimulus for retinal tissue characterisation
10.1364/BODA.2023.JTu4B.5
2023
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Spatio-temporal optical coherence tomography (STOC-T) for high-resolution imaging of the human and mouse retina in vivo
10.1364/BODA.2023.DTh2A.2
2023
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Technical Digest Series
Clinical prototype of multi-spot air-puff OCT for assessment of corneal biomechanical asymmetry
10.1364/BODA.2023.DTh2A.1
2023
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Journal of Clinical Investigation
In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope
10.1016/j.xpro.2023.102225
2023
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SPIE Proceedings
Spatio-temporal optical coherence tomography (STOC-T) focal plane adjustment in the mouse retina aided by a fundus camera
10.1117/12.2652956
2023
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SPIE Proceedings
Frequency characterization of human photoreceptors’ response to light with the use of chirped flicker stimulus optoretinography
10.1117/12.2649632
2023
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SPIE Proceedings
High-speed, in vivo, volumetric imaging of mouse retinal tissue with spatio-temporal optical coherence tomography (STOC-T)
10.1117/12.2648893
2023
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Progress in Retinal and Eye Research
From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation.
10.1016/j.preteyeres.2023.101170
2023
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22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics
Methods of determining the contrast sensitivity function for two-photon vision
10.1117/12.2664174
2022
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Advanced Materials Technologies
Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials
10.1002/admt.202201244
2022
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Technical Digest Series
Functional and Structural Imaging of Retinal Tissue with Spatio-Temporal Optical Coherence Tomography (STOC-T)
10.1364/FIO.2022.FW7D.2
2022
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Biomedical Optics Express
Continuous-wave parallel interferometric near-infrared spectroscopy (CW πNIRS) with a fast two-dimensional camera
10.1364/BOE.472643
2022
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Investigative Ophthalmology & Visual Science
Contrast Sensitivity Function of Two-Photon Vision
https://iovs.arvojournals.org/article.aspx?articleid=2780505
2022
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Investigative Ophthalmology & Visual Science
Towards spectral sensitivity curve for two-photon vision mechanism
https://iovs.arvojournals.org/article.aspx?articleid=2780507
2022
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Investigative Ophthalmology & Visual Science
Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers
https://iovs.arvojournals.org/article.aspx?articleid=2782833
2022
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iScience
Spatio-Temporal Optical Coherence Tomography provides full thickness imaging of the chorioretinal complex
10.1016/j.isci.2022.105513
2022
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Lab on a Chip
You will know by its tail: a method for quantification ofheterogeneity of bacterial populations using single-cell MICprofiling
10.1039/d2lc00234e
2022
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Technical Digest Series
In vivo frequency characterization of human photoreceptors response to a flicker stimulus with optoretinography
10.1364/OCT.2022.CS3E.1
2022
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Biomedical Optics Express
Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system
10.1364/BOE.444567
2022
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Diagnostics
Two-Photon Vision in Age-Related Macular Degeneration: ATranslational Study
10.3390/diagnostics12030760
2022
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Biomedical Optics Express
Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans
10.1364/BOE.452609
2022
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Scientific Reports
Infrared- and white-light retinal sensitivity in glaucomatous neuropathy
10.1038/s41598-022-05718-6
2022
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Optics Letters
Multimode fiber as a tool to reduce crosstalk in Fourier-domain full-field optical coherence tomography
10.1364/OL.449498
2022
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Acta Neurobiologiae Experimentalis
Optical coherence tomography reveals heterogeneity of the brain tissue and vasculature in the ischemic region after photothrombotic stroke in mice
10.55782/ane‑2022‑010
2022
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SPIE BiOS
Air puff-coupled multi-spot OCT for assessment of asymmetries in corneal biomechanics
10.1117/12.2609511
2022
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SPIE Proceedings
Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography
10.1117/12.2609513
2022
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Journal of Clinical Investigation
In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
10.1172/JCI154218
2022
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Investigative Ophthalmology & Visual Science
Pupillary Light Reflex induced by two-photon vision
10.1167/iovs.62.15.23
2021
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Technical Digest Series
Two-photon excited fluorescence scanning laser ophthalmoscope for in vivo imaging of the human eye
10.1364/TRANSLATIONAL.2022.TTu2B.4
2021
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Investigative Ophthalmology & Visual Science
The effect of cataract on two-photon visual thresholds
https://iovs.arvojournals.org/article.aspx?articleid=2775575
2021
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Technical Digest Series
Swept-sources for OCT are perceived due to two-photon vision
10.1117/12.2614850
2021
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APL Photonics
Imaging the small with the small: Prospects for photonics in micro-endomicroscopy for minimally invasive cellular-resolution bioimaging
10.1063/5.0052258
2021
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Optics Letters
Multimode fiber enables control of spatial coherence in Fourier-domain full-field optical coherence tomography for in vivo corneal imaging
10.1364/OL.417178
2021
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SPIE Proceedings
Effects of laser pulse duration in two-photon vision threshold measurements
10.1117/12.2582735
2021
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Biomedical Optics Express
Two-photon microperimetry with picosecond pulses
10.1364/BOE.411168
2020
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Analytical Chemistry
High-Throughput Monitoring of Bacterial Cell Density in Nanoliter Droplets: Label-Free Detection of Unmodified Gram-Positive and Gram-Negative Bacteria
10.1021/acs.analchem.0c03408
2020
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XIII Spanish National Meeting on Optics, Sedoptica
Applications of the ImTOPScanner for the investigation of ocular biomechanical parameters
https://livrepository.liverpool.ac.uk/3141961
2020
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Journal of Biomedical Optics
Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples
10.1117/1.JBO.25.9.096003
2020
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Proceedings of the National Academy of Sciences
Noninvasive two-photon optical biopsy of retinal fluorophores
10.1073/pnas.2007527117
2020
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Biomedical Optics Express
Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities
10.1364/BOE.402402
2020
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Biomedical Optics Express
Longitudinal in-vivo OCM imaging of glioblastoma development in the mouse brain
10.1364/BOE.400723
2020
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Biomedical Optics Express
Frequency-doubled femtosecond Er-doped fiber laser for two-photon excited fluorescence imaging
10.1364/BOE.396878
2020
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Translational Vision Science & Technology
Keratoconus Detection Based on a Single Scheimpflug Image
10.1167/tvst.9.7.36
2020
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Journal of Biophotonics
Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography
10.1002/jbio.202000007
2020
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Optics Letters
Computational aberration correction in spatiotemporal optical coherence (STOC) imaging
10.1364/OL.384796
2020
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Biomedical Optics Express
Crosstalk-free volumetric in vivo imaging of a human retina with Fourier-domain full-field optical coherence tomography
10.1364/BOE.10.006390
2019
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2019 11th International Symposium on Image and Signal Processing and Analysis (ISPA)
Pupil detection supported by Haar feature based cascade classifier for two-photon vision examinations
10.1109/ISPA.2019.8868706
2019
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Biomedical Optics Express
Two-photon microperimetry: sensitivity of human photoreceptors to infrared light
10.1364/BOE.10.004551
2019
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SPIE Proceedings
Solid state versus fiber picosecond infrared lasers applied to two-photon vision tests
10.1117/12.2527118
2019
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Investigative Ophthalmology & Visual Science
The limits of perception of light by two-photon vision
https://iovs.arvojournals.org/article.aspx?articleid=2743619
2019
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Investigative Ophthalmology & Visual Science
The limits of perception of light by two-photon vision
https://iovs.arvojournals.org/article.aspx?articleid=2743619
2019
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Photonics Letters of Poland
Impact of diurnal IOP variations on the dynamic corneal hysteresis measured with air-puff swept-source OCT
10.4302/plp.v10i3.848
2018
2026 
