Past seminar

Single-cell mitochondrial genomics – from lineage tracing to human phenotypes

  • Speaker: PhD Leif S Ludwig

Leif S. Ludwig graduated with a Master of Science (Diploma) and PhD (Dr. rer. nat.) in Biochemistry from the Freie Universitat Berlin and MD from the Charite Universitat&medizin Ber1in. During his Ph□ he worked in the laboratory of Harvey Lodish at the Whitehead Institute for Biomedical Research, functionally lnvestigating how human genetic variation affect human traits and phenotypes, in particular in the context of congenital blood disorders. During his postdoc in the laboratories of Aviv Regev and Vijay Sankaran al the Broad Institute of MIT and Harvard he established single cell sequencing approaches leveraging natural mitochondrial sequence variation to enable the clonal tracing of human cells in a physiologic human context. In November 2020, he started his Emmy Noether research group at the Berlin Institute of Health at Chante and Berlin Institute of Medical Systems Biology at the MDC, where he and his team develop and apply single cell technologies while investigating fundamental properties of mitochoodrial genetics and stem cell dynamics in human hernatopoiesis

About the speaker

Leif S. Ludwig holds a PhD in biochemistry from Freie Universität Berlin and an MD from Charité – Universitätsmedizin Berlin. He leads research on single-cell technologies, mitochondrial genetics and stem-cell dynamics

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