Research details

Image-guided Devices for Ophthalmic Care

Research Group Leader: Karol Karnowski

Coordinator: Dominika Życka-Malesa

The Image-guided Devices for Ophthalmic Care (IDoc) group seeks to research novel techniques and develop instrumentation to address unanswered questions in vision science and unmet needs in ophthalmology and optometry.

The IDoc team members put their experience and know-how in optical engineering, imaging, biomedical physics, computing and mechatronics to work on translational eye research, by collaborating with vision scientists on one side and ophthalmologists, optometrists, and surgeons on the other.

The IDoc laboratory’s research activities focus on the development of:

• Devices for eye function and treatment monitoring

We pioneer new optical techniques and prototype novel devices to monitor eye health and response to treatment for several eye conditions. We do this by imaging dynamically over time the physical response of the eye (and its layers) to external stimuli, such as visible light stimuli and/or mechanical stimuli, for full retinal volumes, on multiple planes sectioning the eye or at an arrangement of locations around the cornea.

• Devices for eye surgery planning

We design and build novel low-cost devices needed for planning eye surgery, especially cataract surgery, such as whole-eye scanners for both the anterior eye segment and the retina and novel ocular biometers, with the goal of increasing accessibility to healthcare.

• Devices for eye surgery guidance and therapy administration

We propose advanced eye tissue visualization with machine vision-enhanced intraoperative OCT and robotic micromanipulation systems for guidance of smart shadowless surgical tools. This aims at delivering safer and more effective eye surgeries and a higher chance to restore vision for those who lost it or never had it.

Contact:
Leader: kkarnowski@ichf.edu.pl

Research Group Leaders & Coordinators

A new paper by IDoc group researchers, international scientists and a spin-off company published in “Biomedical Optics Express”

Extreme macro close-up of a blue iris with detailed fibers around a black pupil on a dark background

20.06.2023

Flicker Optoretinography (f-ORG)

Woman in silver outfit examining an eye through an ophthalmic instrument amid futuristic digital network graphics.

24.03.2023

Multi-spot measurements of air-induced corneal deformations (IMCUSTOMEYE project)

Eye surgeon in scrubs and mask looking through a surgical microscope during an operation

01.10.2021

AIR-PUFF OCT – IMCUSTOMEYE

Yellow pipette tip near test tubes with a DNA double helix and chemical formulas overlay

01.06.2021

Image-guided Devices for Ophthalmic Care

Research Group Leaders & Coordinators

Dominika Życka-Malesa

Karol Karnowski

Doctoral Researchers

Wiktor Kulesza

Research Technicians

Adam Kurek, Eng.

Jadwiga Milkiewicz

Krzysztof Gromada

Tomasz Gawroński

Former members

Andrea Curatolo

Filomena Kowalska

Tomasz Piesio

Publications

Test new SharePoint publication

Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics

Roadmap on Advances in Visual and Physiological Optics

Adaptation of pre-trained single stage detectors for rapid tool pose estimation in OCT-assisted eye surgery

Modeling breast cancer dynamics through modulable small Vessel Environment Bioreactor (sVEB)

Dynamic Corneal Response for Different Air-Puff Stimuli in Ex Vivo Animal Model Measured with SS-OCT System with Two Sample Arms

Imaging of retinal ganglion cells and photoreceptors using Spatio-Temporal Optical Coherence Tomography (STOC-T) without hardware-based adaptive optics

In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography

Multiwavelength laser doppler holography (MLDH) in spatiotemporal optical coherence tomography (STOC-T)

Quantification of smooth muscle in human airways by polarization-sensitive optical coherence tomography requires correction for perichondrium

Long-range frequency-domain optical delay line based on a spinning tilted mirror for low-cost ocular biometry

Optimization-free method for multiple spectrometers alignment in polarization-sensitive optical coherence tomography

Optical beam scanner with reconfigurable non-mechanical control of beam position, angle, and focus for low-cost whole-eye OCT imaging

Flicker optoretinography (f-ORG) with chirped frequency stimulus for retinal tissue characterisation

Spatio-temporal optical coherence tomography (STOC-T) for high-resolution imaging of the human and mouse retina in vivo

A low-cost, non-mechanical optical beam scanner: experimental proof-of-concept for whole-eye OCT imaging

Clinical prototype of multi-spot air-puff OCT for assessment of corneal biomechanical asymmetry

Improved tool tracking algorithm for eye surgery based on combined color space masks

Spatio-temporal optical coherence tomography (STOC-T) focal plane adjustment in the mouse retina aided by a fundus camera

Long-range frequency-domain optical delay line based on a spinning tilted mirror for low-cost ocular biometry

Frequency characterization of human photoreceptors’ response to light with the use of chirped flicker stimulus optoretinography

High-speed, in vivo, volumetric imaging of mouse retinal tissue with spatio-temporal optical coherence tomography (STOC-T)

Intraoperative ophthalmic OCT system tracking surgical tools at 200 Hz

Low-resource and cost-effective camera-based optical palpation for breast cancer detection and burn scar assessment

Estimation of the full shape of the crystalline lens in-vivo from OCT images using eigenlenses

Co-axial acoustic-based optical coherence vibrometry probe for the quantification of resonance frequency modes in ocular tissue

Functional and Structural Imaging of Retinal Tissue with Spatio-Temporal Optical Coherence Tomography (STOC-T)

Superior Imaging Performance of All-Fiber, Two-Focusing-Element Microendoscopes

Design of a low-cost, versatile, whole-eye scanner for optical coherence tomography

Hysteresis in vibrational resonance modes of model corneas measured with Optical Coherence Tomography Vibrography utilizing a co-axial acoustic stimulation technique and pre-compensation

In vivo frequency characterization of human photoreceptors response to a flicker stimulus with optoretinography

Simultaneous multi-spot OCT measurements of air induced corneal deformations

Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system

A novel co-axial and acoustic pre-compensation approach for tissue excitation in optical coherence tomography vibrography

Air puff-coupled multi-spot OCT for assessment of asymmetries in corneal biomechanics

Corneal biomechanical parameters of keratoconus patients from cross-meridian air-puff deformation optical coherence tomography and finite element modeling

Towards spatially mapped frequency response of human photoreceptor length variation with flicker optoretinography

Estimation of scleral mechanical properties from air-puff optical coherence tomography

Imaging the small with the small: Prospects for photonics in micro-endomicroscopy for minimally invasive cellular-resolution bioimaging

Smartphone-based optical palpation: towards elastography of skin for telehealth applications

Improved detection of corneal deformation asymmetries in keratoconus patients using multi-meridian deformation imaging

Applications of the ImTOPScanner for the investigation of ocular biomechanical parameters

Optical Coherence Elastography Imaging Probes

High-frame rate multi-meridian corneal imaging of air-puff induced deformation for improved detection of keratoconus

Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples

Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities

Longitudinal in-vivo OCM imaging of glioblastoma development in the mouse brain

Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography

Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus

Impact of diurnal IOP variations on the dynamic corneal hysteresis measured with air-puff swept-source OCT

More than a number. How IOP really shapes vision

All fiber imaging probes

Anterior segment structural and functional imaging

Ultrahigh resolution OCT

Scanning OCT system for animal model study

Surgery guidance and therapy administration

IDoc Group achievements in 3 years perspective

A new paper by IDoc group researchers, international scientists and a spin-off company published in “Biomedical Optics Express”

Flicker Optoretinography (f-ORG)

Multi-spot measurements of air-induced corneal deformations (IMCUSTOMEYE project)

AIR-PUFF OCT – IMCUSTOMEYE

Telehealth applications