Sathi Goswami, PhD
PhD degree in biophysical chemistry from Saha Institute of Nuclear Physics, University of Calcutta, India
Post-doc
Description
Dr. Sathi Goswami obtained her PhD in biophysical chemistry from Saha Institute of Nuclear Physics, under the University of Calcutta, Kolkata, India in 2018. During her PhD she studied the interaction of non-steroidal anti-inflammatory drugs and their metal complexes with DNA and proteins through spectroscopic and imaging studies. She also studied the effect of these drugs and complexes on standard cancer cells HeLa to demonstrate the changes in the epigenetic level.
Then she joined as a postdoctoral fellow at Indian Institute of Technology Bombay, Maharashtra, India in 2018. In postdoctoral studies her research was focused on the characterization of drug-protein interaction using different spectroscopy. In September 2022, she joined Integrated Structural Biology lab at ICTER as a postdoctoral fellow to work on the structure and functions of various proteins involved in the visual cycle.
Publication list
- S. Goswami, R. Ghosh, P. Prasanthan, N. Kishore, “Mode of interaction of altretamine with calf thymus DNA: biophysical insights,” Journal of Biomolecular Structure and Dynamics, 41, 3728-3740, (2022)
- S. Goswami, M. Sarkar, “Fluorescence, FTIR and 1H NMR studies of the inclusion complexes of the painkiller lornoxicam with β-, γ-cyclodextrins and their hydroxy propyl derivatives in aqueous solutions at different pHs and in the solid state,” New Journal of Chemistry, 42, 15146-15156, (2018)
- S. Goswami, S. Sanyal, P. Chakraborty, C. Das, M. Sarkar, “Interaction of a Common Painkiller Piroxicam and Copper-piroxicam with Chromatin Causes Structural Alterations Accompanied by Modulation at the Epigenomic/Genomic level,” Biochimica et Biophysica Acta (BBA) – General Subjects, 1861, 2048-2059, (2017)
- S. Goswami, A. Majumdar, M. Sarkar, “Painkiller Isoxicam and Its Copper Complex Can Form Inclusion Complexes with Different Cyclodextrins: A Fluorescence, Fourier Transform Infra Red Spectroscopy and Nuclear Magnetic Resonance Study,” Journal of Physical Chemistry B, 121, 8454-8466, (2017)
- S. Goswami, S. Ray, M. Sarkar, “Spectroscopic Studies on the Interaction of DNA with the Copper Complexes of NSAIDs Lornoxicam and Isoxicam,” International Journal of Biological Macromolecules, 93, 47-56, (2016)
Research projects
Research groups
Integrated Structural Biology
Research aims to elucidate the mechanisms of vision, particularly proteins of the phototransduction pathway and the visual cycle, at an atomic and molecular level.
