Physical Optics and Biophotonics

How to see the invisible? The limits of two-photon vision
11.05.2026

How to see the invisible? The limits of two-photon vision

Near-infrared light is invisible to humans. And yet, under the right conditions, the human eye can perceive it. Researchers from the International Centre for Translational Eye Research (ICTER) have now shown that the efficiency of this phenomenon depends not only on the laser pulse itself, but also on two highly specific factors: the beam diameter […]

ICTER contributes to a global handbook of visual optics
21.04.2026

ICTER contributes to a global handbook of visual optics

Researchers from ICTER are among the authors of the latest volume of the Handbook of Visual Optics, edited by Prof. Pablo Artal – one of the most important contemporary references on vision technology and ophthalmic diagnostics.

Two-photon Vision in AR glasses. ICTER is developing a completely new class of displays
16.12.2025

Two-photon Vision in AR glasses. ICTER is developing a completely new class of displays

A prototype is being created in ICTER’s laboratories that may redefine how we build augmented reality. The team led by Dr. Eng. Katarzyna Komar is developing AR glasses that use two-photon vision. This mechanism enables bright, sharp, and high-contrast images without complicating the optics and without the typical limitations of today’s solutions.

Abstract futuristic technology background with glowing blue and magenta polygonal shapes on dark
28.08.2023

Diffuse optics and interferometry

Diffuse optics offers a noninvasive portable approach for examining biological tissues, including the human brain, in vivo [1]. Near-infrared spectroscopy (NIRS) [2] and diffuse correlation spectroscopy (DCS) are the primary diffuse optical modalities [3, 4]. In both approaches, the light illuminates the tissue, and diffusively scattered photons are collected at some distance from the emitter […]

Abstract futuristic dark background with blue and magenta digital dot patterns and a lens flare
20.06.2023

Flicker Optoretinography (f-ORG)

For many years visual inspection of fundus photography [1] and examination of images acquired with optical coherence tomography (OCT) [2] have been used by ophthalmologists for eye disease diagnosis and monitoring therapy progress thanks to their ability to detect morphological changes in the retina. However, imaging the morphological manifestation of retinal diseases alone does not provide sufficient […]

<strong>Two-Photon Excited-Fluorescence Scanning Laser Ophthalmoscope (TPEF-SLO)</strong>
15.06.2023

Two-Photon Excited-Fluorescence Scanning Laser Ophthalmoscope (TPEF-SLO)

The ability to noninvasively access metabolic processes during the visual cycle is crucial for developing therapies against retinal degenerative diseases. We have developed a protocol for obtaining in vivo two-photon excited fluorescence images of the fundus in the human eye. The visual cycle is a series of chemical transformations during which various fluorescent intermediates are […]

Two-photon vision
06.06.2023

Two-photon vision

Vision allows for receiving stimuli from the surrounding world through electromagnetic waves from 400 to 780 nm, called visible light. It begins when a photon of such light is absorbed by the visual pigment of the photoreceptor in the light-sensitive part of the eye – the retina. Absorption of a photon initiates a series of […]

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