A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models

Leinonen H, Zhang J, Occelli LM, Seemab U, Choi EH, L P Marinho LF, Querubin J, Kolesnikov AV, Galinska A, Kordecka K, Hoang T, Lewandowski D, Lee TT, Einstein EE, Einstein DE, Dong Z, Kiser PD, Blackshaw S, Kefalov VJ, Tabaka M, Foik A, Petersen-Jones SM, Palczewski K.

Nature Communications, 15(1):5943

DOI: 10.1038/s41467-024-50033-5.

Autorzy ICTER: Anna Galińska, Marcin Tabaka, Andrzej Foik

Research groups: Ophthalmic Biology Laboratory, Computational Genomics Group

Granty: SONATA BIS 9 / NCN, SONATA 16 / NCN